The History of FOP

Fop has always been a thing, though it only got our attention now because of the large amount of the population. The first documented case of FOP is from a French physician Guy Patin, who described seeing a man who was "Turning into stone", in 1692. In 1900, the disease was officialy given the name, Myotosis ossificans progressiva. This name was changed to Fibrodysplaisia ossficans progressiva in the 1970s after the late Dr. Victor Mckusick found out it did not only affect muscles but rather all fibrous tissue.

Only recently have there been any major breakthroughs about FOP, but these recent breakthrough have sparked over 15 clinical trials for a cure or at least something that would prevent FOP. in 2006, researchers looking for a breakthrough for FOP found one: this breakthrough was the cause of FOP, which until then, had no exact known origin. This cause was a random genetic mutation in the ACVR1 gene, which caused it to interact with activin and create a wave of ACVR1 proteins that began to turn different areas around the body.

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